HLA Tissue Typing Menu

Molecular Diagnostics Laboratory is accredited for histocompatibility testing by the American Society of Histocompatibility and Immunogenetics (ASHI).

Molecular Diagnostics Laboratory has the capability to perform HLA testing for multiple indications, including:

  • Solid Organ and Bone Marrow Transplantation
  • Engraftment Monitoring
  • Disease Association
  • Vaccine Development
  • Immunotherapy
  • Drug Sensitivity

Molecular Diagnostics Laboratory offers several methodologies to establish HLA antigens (HLA-A, -B, -C, -DRB1/3/4/5, -DQA, -DQB, -DPA, -DPB and HLA antibodies:

  • Next-Generation Sequencing HLA Typing (High-Resolution)
  • Real-Time PCR Melt-Curve Analysis HLA Typing (Intermediate-Resolution)
  • DNA Sequence Specific Oligonucleotide Probe (SSOP) Typing (Intermediate-Resolution)
  • Engraftment Studies (Chimerisms) via STR Analysis
  • Donor/Recipient Crossmatching
  • HLA-Antibody Screening and Single Antigen Assessment