HLA Tissue Typing Menu


Molecular Diagnostics Laboratory is accredited for histocompatibility testing by the American Society of Histocompatibility and Immunogenetics (ASHI) (certifications & accreditations).


Molecular Diagnostics Laboratory has the capability to perform HLA testing for multiple indications, including:

  • Solid Organ and Bone Marrow Transplantation
  • Engraftment Monitoring
  • Disease Association
  • Vaccine Development
  • Immunotherapy
  • Drug Sensitivity

Molecular Diagnostics Laboratory offers several methodologies to establish HLA antigens (HLA-A, -B, -C, -DRB1/3/4/5, -DQA, -DQB, -DPA, -DPB and HLA antibodies:

  • Next-Generation Sequencing HLA Typing (High-Resolution)
  • Real-Time PCR Melt-Curve Analysis HLA Typing (Intermediate-Resolution)
  • DNA Sequence Specific Oligonucleotide Probe (SSOP) Typing (Intermediate-Resolution)
  • Engraftment Studies (Chimerisms) via STR Analysis
  • Donor/Recipient Crossmatching
  • HLA-Antibody Screening and Single Antigen Assessment